abstract：:The evolution of strategies for the use of spironolactone and its analogue, eplerenone, has, over the years, encompassed favourable modification of the natural history of symptomatic heart failure in subjects with subnormal left ventricular ejection fraction (LVEF), and mitigation of the risk of new-onset atrial fibri...

journal_title：European journal of internal medicine

authors： Jolobe OM

更新日期：2013-06-01 00:00:00

abstract：:Within a few decades half of the patients with non-valvular atrial fibrillation (AF) will be older than 80 years. These patients are at particularly high risk of thromboembolism (Scylla) but also of the hemorrhagic complications of thromboprophylaxis (Charybdis). A frequent compromise is to use as antithrombotic agent...

journal_title：European journal of internal medicine

authors： Mannucci PM

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) is frequent in elderly patients, but few studies have focused on patients older than 84 years. The aim of this study was to evaluate major comorbidities and 1-year survival in HF patients aged ≥85 years compared with younger age groups. METHODS:Patients included in a prospective national ...

journal_title：European journal of internal medicine

authors： Conde-Martel A,Formiga F,Pérez-Bocanegra C,Armengou-Arxé A,Muela-Molinero A,Sánchez-Sánchez C,Diez-Manglano J,Montero-Pérez-Barquero M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Patients with heart failure with preserved ejection fraction (HFPEF) represent an important group of patients presenting in clinical practice. However, whether it is an earlier stage of heart failure with reduced ejection fraction (HFREF) remains uncertain. We evaluated the potential progression of HFPEF to ...

journal_title：European journal of internal medicine

authors： Páez-Rubio MI,Carrasco-Sánchez FJ,Escobar-Cervantes C,Sánchez-Gómez N,Santiago-Ruiz JL,Yebra-Yebra M,Manzano L

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:The low pharmacological response to phosphodiesterase type 5 inhibitors represents an expression of higher endothelial damage in certain categories of patients with erectile dysfunction and high cardiovascular risk. The present study evaluated this objective in type 2 diabetic patients with erectile dysfunct...

journal_title：European journal of internal medicine

authors： Condorelli RA,Calogero AE,Favilla V,Morgia G,Johnson EO,Castiglione R,Salemi M,Mongioí L,Nicoletti C,Duca Y,Di Mauro M,Vicari E,La Vignera S

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND & AIMS:There is limited data comparing influence of age on the presentation, clinical course, and therapeutic response of patients with ulcerative colitis. We aimed to compare the demographic and clinical characteristics of patients diagnosed with UC in older age vs. adulthood vs. early age. METHODS:Five-hu...

journal_title：European journal of internal medicine

authors： Kalkan IH,Dağli U,Oztaş E,Tunç B,Ulker A

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Sex related differences in cardiovascular disease and stroke are issues of increasing interest. The aim of this study was to evaluate for sex differences in clinical presentation, severity of stroke and outcome in a population of patients admitted to 4 public and 1 private hospitals in three diff...

journal_title：European journal of internal medicine

authors： Santalucia P,Pezzella FR,Sessa M,Monaco S,Torgano G,Anticoli S,Zanoli E,Maimone Baronello M,Paciaroni M,Caso V,Women Stroke Association (WSA).

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Vascular endothelium activation is a key pathogenic step in systemic inflammatory response syndrome (SIRS) that can be triggered by both microbial and sterile proinflammatory stimuli. The relevance of soluble adhesion molecules as clinical biomarkers to discriminate between infectious and non-infectious SIRS...

journal_title：European journal of internal medicine

authors： de Pablo R,Monserrat J,Reyes E,Díaz D,Rodríguez-Zapata M,de la Hera A,Prieto A,Álvarez-Mon M

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Medication reconciliation process has proved to be an effective tool to improve the safety of drug use. The objective of this study was to assess the impact of an intervention aimed to decrease unintended discrepancies between patient's usual treatment and medications prescribed on admission to the Departmen...

journal_title：European journal of internal medicine

authors： Zoni AC,Durán García ME,Jiménez Muñoz AB,Salomón Pérez R,Martin P,Herranz Alonso A

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Hepatitis B virus infection has decreased in Italy. The aims of this study were to identify changes, if any, in the epidemiological pattern of HBV infection in a southern Italian town first surveyed in 1996 and to assess the effectiveness of vaccination campaign against hepatitis B. METHODS:In 2010, subject...

journal_title：European journal of internal medicine

authors： Stroffolini T,Guadagnino V,Rapicetta M,Menniti Ippolito F,Caroleo B,De Sarro G,Focà A,Liberto MC,Giancotti A,Barreca GS,Marascio N,Lombardo F,Staltari O,Sersale's Study Collaborating Group.

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Prognostic factors of mortality in elderly patients with dementia with aspiration pneumonia (AP) are scarcely known. We determined the mortality rate and prognostic factors in old patients with dementia hospitalized due to AP. METHODS:We prospectively studied 120 consecutive patients aged ≥ 75 years with de...

journal_title：European journal of internal medicine

authors： Bosch X,Formiga F,Cuerpo S,Torres B,Rosón B,López-Soto A

更新日期：2012-12-01 00:00:00

abstract：:Stroke is a leading cause of death worldwide and the first cause of disability in the Western world. Over the last 20 years, antiplatelet agents have reduced overall stroke rates in primary and secondary prevention in men. However, this has not been the case for women. In this narrative review, the most widely used an...

journal_title：European journal of internal medicine

authors： Caso V,Santalucia P,Acciarresi M,Pezzella FR,Paciaroni M

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Visceral obesity increases the risk of arterial hypertension (78% of cases of hypertension in men and 65% of cases in women). The aim of the study is to assess the role of visceral obesity in causing resistant hypertension (RH). METHODS:The survey was performed on 5065 hypertensive patients with visceral ob...

journal_title：European journal of internal medicine

authors： Holecki M,Duława J,Chudek J

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:To assess the prevalence of decreased iron stores and anemia in pregnant women. To determine whether the risk factors: socio-demographic background, age, BMI, and parity are associated with abnormal hemoglobin concentrations and/or abnormal iron status. METHODS:A longitudinal study was carried out at the De...

journal_title：European journal of internal medicine

authors： Bencaiova G,Burkhardt T,Breymann C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The epidemiological pattern of hepatitis B virus infection in Italy has greatly changed over the past decades. The aim of the study was to evaluate during time the epidemiological features of acute hepatitis B cases referred to an Infectious Disease Unit in North-East of Italy between 1978 and 1995. PATIENT...

journal_title：European journal of internal medicine

authors： Stroffolini T,Rapicetta M,Lombardo F,Chionne P,Madonna E,Candido A,Taffon S,Rinaldi R,Ermg E,Bortolotti F

更新日期：2012-09-01 00:00:00

abstract：:The use of non-invasive ventilation in patients with community-acquired pneumonia is controversial since this is associated with high rates of treatment failure, compared with other causes of severe acute respiratory failure. The populations of patients with community-acquired pneumonia who have demonstrated better re...

journal_title：European journal of internal medicine

authors： Ferrer M,Cosentini R,Nava S

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Statins are the treatment of choice for lowering LDL-C levels and reducing cardiovascular events. They have a remarkable safety profile, although some patients do not tolerate them. The aim of the study was to summarize the existing data on non-every day statin administration regimens. METHODS:We searched t...

journal_title：European journal of internal medicine

authors： Elis A,Lishner M

更新日期：2012-07-01 00:00:00

abstract：:Venous and arterial thromboses have traditionally been regarded as separate diseases with different causes. However, recent epidemiological studies have documented an association between these vascular complications, probably due to the presence of more overlapping risk factors than previously recognized. This narrati...

journal_title：European journal of internal medicine

authors： Franchini M,Mannucci PM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:After an acute pulmonary embolism (PE), the complete resolution of thromboemboli may not be routinely achieved. The rate of persistence may depend on the time and the diagnostic technique used for evaluation. PATIENTS AND METHODS:Patients were diagnosed with acute PE by means of computed tomography angiogra...

journal_title：European journal of internal medicine

authors： Alonso-Martínez JL,Anniccherico-Sánchez FJ,Urbieta-Echezarreta MA,García-Sanchotena JL,Herrero HG

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Mallory-Weiss syndrome is defined by upper gastrointestinal bleeding from vomiting-induced mucosal lacerations at the esophago-gastric junction. This study was purposed to investigate the incidence, location, clinical manifestation, diagnosis and effectiveness of treatment (including endoscopic treatment and...

journal_title：European journal of internal medicine

authors： Yin A,Li Y,Jiang Y,Liu J,Luo H

更新日期：2012-06-01 00:00:00

abstract：:Venous thromboembolism (VTE) is frequent in patients hospitalized in Internal Medicine wards. It carries a considerable morbidity and mortality. Recommendations for use of anticoagulation are graded 1A in leading evidence-based consensus guidelines. Implementation of these guidelines is suboptimal. Lack of awareness s...

journal_title：European journal of internal medicine

authors： Roth-Yelinek B

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Diabetes mellitus can cause a wide variety of vascular complications and it is one of the major risk factors for cardiovascular diseases (CVD). High glucose can induce vascular endothelial cell apoptosis. In this study, we investigated the effect of radix hedysari polysaccharide (HPS) on the depression of ap...

journal_title：European journal of internal medicine

authors： Liu J,Deng W,Fan L,Tian L,Jin L,Jin Z,Guo Q,Xu Y,Li N

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The role of estrogen receptor α (ERα) polymorphism in coronary artery disease (CAD) was investigated previously in several populations. There are few data on relation between ERa polymorphism and CAD in Chinese population. Our study was to investigate the possible association between ERα polymorphism and CAD...

journal_title：European journal of internal medicine

authors： Shen C,Chen J,Fan S,Li Z,Hu Y,Zhong Q

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether...

journal_title：European journal of internal medicine

authors： Zöller B,Li X,Sundquist J,Sundquist K

更新日期：2012-01-01 00:00:00

abstract：SUMMARY:Diabetes mellitus (DM) has been declared as a global public health threat to society. However, the burden of the disease in elderly Asian patients has not been described. The aim of the study is to assess the disease burden of DM and its associated adverse outcomes in elderly patients from an Asian hospital usi...

journal_title：European journal of internal medicine

authors： Yang Y,Goh SY,Tan SB,Ho HJ,Emmanuel S,Wang P,Ng HS

更新日期：2012-01-01 00:00:00

abstract：:The rising incidence of Clostridium difficile (C. difficile) infection or CDI is now a problem of pandemic proportions. The NAP1 hypervirulent strain of C. difficile is responsible for a majority of recent epidemics and the widespread use of fluoroquinolone antibiotics may have facilitated the selective proliferation ...

journal_title：European journal of internal medicine

authors： Pant C,Sferra TJ,Deshpande A,Minocha A

更新日期：2011-12-01 00:00:00

abstract：SUMMARY:The aims of this study were to determine the incidence of fungal infections in hospital intensive care units and to evaluate a molecular method to detect these infections. MATERIAL AND METHODS:The participants in this study were patients admitted to any of the 10 intensive care units at Nemazi Hospital (Shiraz...

journal_title：European journal of internal medicine

authors： Badiee P,Alborzi A,Joukar M

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Proteinuria is a common presentation of mesangioproliferative glomerulonephritis (MsPGN). No studies are available on the long-term effect of treatment by renin-angiotensin system (RAS) inhibitors on renal outcome in MsPGN patients. This study prospectively evaluates the effects of RAS inhibitors on renal ou...

journal_title：European journal of internal medicine

authors： Presta P,Minutolo R,Iodice C,Comi N,Casoria V,Fuiano L,Caglioti C,Conte G,Fuiano G

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:While the promotion of health-related fitness is thereby widespread, less focus is currently being given on the biological influence that physical activity might exert on results of laboratory testing. As such, this study was undertaken to assess the kinetics of liver injury markers following physical exerci...

journal_title：European journal of internal medicine

authors： Lippi G,Schena F,Montagnana M,Salvagno GL,Banfi G,Guidi GC

更新日期：2011-10-01 00:00:00

abstract：:Portopulmonary hypertension is a form of pulmonary arterial hypertension that has gained interest in recent years with the development of liver transplantation techniques and new pulmonary vasodilator therapies. Portopulmonary hypertension is defined as pulmonary artery hypertension associated with portal hypertension...

journal_title：European journal of internal medicine

authors： Giusca S,Jinga M,Jurcut C,Jurcut R,Serban M,Ginghina C

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:We aimed to evaluate the presence of nocturnal hypotension (NHP) in ischemic stroke (IS) survivors using ambulatory blood pressure (BP) monitoring (ABPM). METHODS:We included fifty consecutive patients presenting at our outpatient clinic for review and who had been discharged for IS in the previous six mont...

journal_title：European journal of internal medicine

authors： Castilla-Guerra L,Fernández-Moreno Mdel C,Espino-Montoro A,López-Chozas JM

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Apolipoproteins AI-CIII-AIV play important roles in the metabolism of triglycerides and high-density lipoprotein cholesterol. However, whether genetic variations in the ApoAI-CIII-AIV gene cluster are associated with the risk of myocardial infarction (MI) remains uncertain. In the present study, we examined ...

journal_title：European journal of internal medicine

authors： Sediri Y,Kallel A,Feki M,Mourali S,Elasmi M,Abdessalem S,Mechmeche R,Jemaa R,Kaabachi N

更新日期：2011-08-01 00:00:00

abstract：:The European School of Internal Medicine (ESIM) is a meeting aimed at young physicians training in internal medicine throughout Europe. Since 1998 the school has been held annually, and in this report we reflect on our experiences during the recent school in Brighton in July 2010. The school combined a broad mix of le...

journal_title：European journal of internal medicine

authors： Hewitt S,Weidanz F,Westgeest H,Ruza I,Ciferska H,Pasquet F,Salomäki S,Olsen E

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Cranial nerve involvement is commonly observed in patients with tuberculous meningitis. The present study evaluated the incidence, predictors and prognostic significance of cranial nerve involvement in tuberculous meningitis. MATERIALS AND METHOD:One hundred-fifty-eight adult patients with tuberculous menin...

journal_title：European journal of internal medicine

authors： Sharma P,Garg RK,Verma R,Singh MK,Shukla R

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND/AIM:The spontaneous preterm birth (SPB) rates in a group of HBeAg-negative chronic HBV infected pregnant women without several known risk factors for preterm delivery as well as the mother to infant HBV transmission rates was evaluated. Moreover the role of maternal data during perinatal period as well as th...

journal_title：European journal of internal medicine

authors： Elefsiniotis IS,Tsoumakas K,Papadakis M,Vlachos G,Saroglou G,Antsaklis A

更新日期：2011-04-01 00:00:00

abstract：:Cardiac resynchronization therapy (CRT) is an established treatment for refractory chronic heart failure (CHF) patients with ventricular dyssynchrony. The patient selection for this therapy remains the basis for response improvement. Various parameters, methods and technology for identification of appropriate patient ...

journal_title：European journal of internal medicine

authors： Geng J,Wu B,Zheng L,Zhu J

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Peripheral arterial disease (PAD) in the aortoiliac segment is found in nearly a half of patients with PAD. The aim of this study was to estimate the influence of obesity and fat distribution on the occurrence of aortoiliac PAD in middle-aged men. METHODS:This case-control study included 204 middle-aged men...

journal_title：European journal of internal medicine

authors： Jakovljević B,Stojanov V,Lović D,Paunović K,Radosavljević V,Tutić I

更新日期：2011-02-01 00:00:00

abstract：:All major antihypertensive drug classes i.e. diuretics, beta-blockers, calcium antagonists and blockers of the renin-angiotensin system have been shown to effectively lower blood pressure and hence to reduce cardiovascular outcomes in hypertensive patients. These drugs decrease cardiovascular complications in hyperten...

journal_title：European journal of internal medicine

authors： Forni V,Wuerzner G,Pruijm M,Burnier M

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:To describe the clinical characteristics and evolution of a series of adult patients hospitalized for neuro-Behçet disease (NBD). METHODS:Consecutive patients admitted for NBD in a teaching hospital were retrospectively selected. Disability at discharge and during follow-up was graded with the modified Rank...

journal_title：European journal of internal medicine

authors： Riera-Mestre A,Martínez-Yelamos S,Martínez-Yelamos A,Ferrer I,Pujol R,Vidaller A

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Upper gastrointestinal bleeding is the severe complication of stress-related mucosal disease in hospitalized patients. In intensive care units (ICU), risk factors are well defined and only mechanical ventilation and coagulopathy proved to be relevant for significant bleeding. On the contrary, in non-ICU sett...

journal_title：European journal of internal medicine

authors： Amaral MC,Favas C,Alves JD,Riso N,Riscado MV

更新日期：2010-10-01 00:00:00